2-Methylbenzoyl chloride → HCID 67479159, compound

HRID 1027442Notes

Reaction equation

HRID 1027442 reaction equation
[CH3:1][C@H:2]1[CH2:6][CH2:5][CH2:4][N:3]1[CH:7]1[CH2:11][CH2:10][C@H:9]([C:12]2[CH:17]=[CH:16][C:15]([NH2:18])=[CH:14][CH:13]=2)[CH2:8]1.[CH3:19][C:20]1[CH:28]=[CH:27][CH:26]=[CH:25][C:21]=1[C:22](Cl)=[O:23]>>[CH3:19][C:20]1[CH:28]=[CH:27][CH:26]=[CH:25][C:21]=1[C:22]([NH:18][C:15]1[CH:16]=[CH:17][C:12]([C@H:9]2[CH2:10][CH2:11][CH:7]([N:3]3[CH2:4][CH2:5][CH2:6][C@@H:2]3[CH3:1])[CH2:8]2)=[CH:13][CH:14]=1)=[O:23]

Participants

3

Reactant 2

HCID 702762-Methylbenzoyl chlorideHCID 674791474-[(S)-3-((S)-2-Methyl-pyrrolidin-1-yl)-cyclopentyl]-phenylamine2×

Product 1

HCID 67479159HCID 67479159, compound

Procedure

The title compound was synthesized essentially in the same manner as Example 28 by employing 4-[(S)-3-((S)-2-methyl-pyrrolidin-1-yl)-cyclopentyl]-phenylamine (Intermediate 14) and 2-methylbenzoyl chloride.

Sources & evidence

ORD record
ord-01601acfa5944338ac9a134a4cd01f32
Source dataset
uspto-grants-2014_05
Patent number
US08735385B2

Reaction notes

Loading…