Phenylacetyl chloride → HCID 67478864, compound

HRID 1027446Notes

Reaction equation

HRID 1027446 reaction equation
[CH3:1][C@H:2]1[CH2:6][CH2:5][CH2:4][N:3]1[CH:7]1[CH2:11][CH2:10][C@H:9]([C:12]2[CH:17]=[CH:16][C:15]([NH2:18])=[CH:14][CH:13]=2)[CH2:8]1.[CH:19]1[CH:24]=[CH:23][C:22]([CH2:25][C:26](Cl)=[O:27])=[CH:21][CH:20]=1>>[CH3:1][C@H:2]1[CH2:6][CH2:5][CH2:4][N:3]1[CH:7]1[CH2:11][CH2:10][C@H:9]([C:12]2[CH:17]=[CH:16][C:15]([NH:18][C:26](=[O:27])[CH2:25][C:22]3[CH:23]=[CH:24][CH:19]=[CH:20][CH:21]=3)=[CH:14][CH:13]=2)[CH2:8]1

Participants

3

Reactant 2

HCID 7679Phenylacetyl chlorideHCID 674791474-[(S)-3-((S)-2-Methyl-pyrrolidin-1-yl)-cyclopentyl]-phenylamine2×

Product 1

HCID 67478864HCID 67478864, compound

Procedure

The title compound was synthesized essentially in the same manner as Example 28 by employing 4-[(S)-3-((S)-2-methyl-pyrrolidin-1-yl)-cyclopentyl]-phenylamine (Intermediate 14) and phenacetyl chloride.

Sources & evidence

ORD record
ord-c6cdfb8f2db0469284b2077feae0c6f0
Source dataset
uspto-grants-2014_05
Patent number
US08735385B2

Reaction notes

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