2-Bromoethanol → HCID 58382523, compound

Participants

Reaction Conditions

Reaction Steps

130 mg of potassium carbonate and 32.4 mg of 2-bromo-ethanol were added to a solution of 100 mg of 4-[5-(4-chloro-benzyl)-7-propoxy-oxazolo[5,4-d]pyrimidin-2-yl]2,6-dimethyl-phenol in 3 ml of dimethylformamide. The reaction mixture was heated to 60° C. for 3 h. After filtration, the solvent was removed in vacuo. Preparative HPLC (method HPLC1) of the residue yielded 5.4 mg of the title compound.

Provenance & Evidence