HCID 86656417, compound → HCID 178467402, compound

Participants

Reaction Steps

A solution of 300 mg of 5-(4-chloro-benzyl)-2-(3,5-dimethyl-4-oxiranylmethoxy-phenyl)-7-ethoxy-oxazolo[5,4-d]pyrimidine (prepared analogously as described in example 20, step (a)) and 92 mg of 5-isopropyl-4H-[1,2,4]triazole-3-thiol in 3 ml of dimethylformamide was heated for 2 h to 130° C. in a microwave reactor. After removal of the solvent the product was isolated by preparative HPLC (method HPLC1) to yield 89 mg of the title compound.

Provenance & Evidence