HCID 178450299, compound → HCID 178450301, compound

HRID 1027524Notes

Reaction equation

HRID 1027524 reaction equation
[CH2:1]([O:5][C:6]1[C:7]([C:11]2[CH:12]=[N:13][CH:14]=[CH:15][CH:16]=2)=[N:8][NH:9][CH:10]=1)[CH2:2][CH2:3][CH3:4].[CH3:17]SC1C(C2C=NC=CC=2)=NNC=1>>[CH2:1]([O:5][C:6]1[C:7]([C:11]2[CH2:12][N:13]([CH3:17])[CH2:14][CH2:15][CH:16]=2)=[N:8][NH:9][CH:10]=1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 178450299HCID 178450299, compoundHCID 178503312HCID 178503312, compound

Product 1

HCID 178450301HCID 178450301, compound

Procedure

Compound 32C was converted to the title compound (33C), using the methodology described for the conversion of 21A to 22A (see Scheme 3).

Sources & evidence

ORD record
ord-c9e060e3320a4fb6bb2c9d72f67bf7e1
Source dataset
uspto-grants-2014_05
Patent number
US08735388B2

Reaction notes

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