Isoamyl mercaptan → HCID 178447694, compound

HRID 1027551Notes

Reaction equation

HRID 1027551 reaction equation
[CH2:1]([S:6][C:7]1[C:8]([CH:12]2[CH:17]3[CH2:18][CH2:19][N:14]([CH2:15][CH2:16]3)[CH2:13]2)=[N:9][NH:10][CH:11]=1)[CH2:2][CH2:3][CH2:4]C.[CH3:20]C(C)CCS>>[CH3:20][CH:3]([CH3:4])[CH2:2][CH2:1][S:6][C:7]1[C:8]([CH:12]2[CH:17]3[CH2:16][CH2:15][N:14]([CH2:19][CH2:18]3)[CH2:13]2)=[N:9][NH:10][CH:11]=1

Participants

3

Reactant 2

HCID 10925Isoamyl mercaptanHCID 178447695HCID 178447695, compound

Product 1

HCID 178447694HCID 178447694, compoundYield 20%

Procedure

Compound 49H was prepared following the procedure as described for the synthesis of compound 49B (see Scheme 10) using 3-methyl-1-butanethiol as reagent. Subsequent purification by flash chromatography (EtOH) afforded compound 49G.

Workup

  1. customSubsequent purification by flash chromatography (EtOH)

Sources & evidence

ORD record
ord-30b8260fb3b64a35b5f2f9f1540be6c1
Source dataset
uspto-grants-2014_05
Patent number
US08735388B2

Reaction notes

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