Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | HCID 86621900 | HCID 86621900 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 86621899 | HCID 86621899 | — |
Reaction Steps
The product from Example 83A (20 mg, 0.051 mmol) was treated with CHCl3 (0.080 mL), pyridine (0.020 mL, 0.25 mmol), and acetic anhydride (0.006 mL, 0.061 mmol), then heated at 60° C. overnight, cooled and purified by chromatography (eluting with 9:1, 4:1 and 2:1 CH2Cl2:EtOAc) to provide the title compound. MS (M+H)+ m/z 438.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08735411B2 |
|---|
| Source dataset | uspto-grants-2014_05 |
|---|
| ORD ID | ord-d8bea1f420c044698819d7d668f4c8b0 |
|---|
| Source note | uspto-grants-2014_05 |
|---|
