Methanol → 1-(Methylamino)-3-(pyrrolidin-1-yl)propan-2-ol

HRID 102801Notes

Reaction equation

HRID 102801 reaction equation
[C+4:21].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[CH2:8][NH:9][CH2:10][CH:11]([CH2:12][N:13]1[CH2:14][CH2:15][CH2:16][CH2:17]1)[OH:18].[CH3:19][OH:20].[OH-:22].[OH-:24].[OH-:25].[OH-:26].[OH-:27].[OH-:28].[Pd+2:23]>>[CH3:8][NH:9][CH2:10][CH:11]([CH2:12][N:13]1[CH2:14][CH2:15][CH2:16][CH2:17]1)[OH:18]

Participants

6

Reactant 5

HCID 887MethanolHCID 961Hydroxide6×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 23153227HCID 23153227, compoundHCID 178420935HCID 178420935, compound

Product 1

HCID 225620281-(Methylamino)-3-(pyrrolidin-1-yl)propan-2-ol

Sources & evidence

ORD record
ord-3442ab8a870f4f128211e0b02291239c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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