HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → Tert-butyl 6,6-dimethyl-4-oxo-4,6-dihydrofuro[3,4-d]thiazol-2-ylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | Diisopropylamine | HCID 7912 | — |
| Reactant | Methyl 2-Boc-aminothiazole-4-carboxylate | HCID 7213137 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Product | Tert-butyl 6,6-dimethyl-4-oxo-4,6-dihydrofuro[3,4-d]thiazol-2-ylcarbamate | HCID 86618914 | — |
Reaction Steps
Methyl 2-(tert-butoxycarbonylamino)thiazole-4-carboxylate (purchased from Combi-Blocks), diisopropylamine, butyllithium, and dry acetone (purchased from Acros) were processed as described in Example 3D to obtain the title compound. MS (ESI+) m/z 285 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08735434B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-f5cbc1753cb04780bdc5976ae0439063 |
| Source note | uspto-grants-2014_05 |