Methyl 2-(1,4-dioxaspiro[4.5]decan-8-ylidene)acetate → Methyl 2-(1,4-dioxaspiro[4.5]decan-8-yl)acetate

Participants

Reaction Steps

An ethanol (50 mL) suspension of (1,4-dioxa-spiro[4.5]dec-8-ylidene)-acetic acid methyl ester (6.57 g) obtained in Example (1a) and palladium carbon (10% by weight) was hydrogen-reduced at room temperature for 24 hours. The reaction mixture was filtered and concentrated. The residue was purified by chromatography (hexane/ethyl acetate=5:1) to obtain the title compound (4.99 g, 75%) as a colorless oil.

Provenance & Evidence