Sodium Hydroxide → 3-(Ethylhydroxyphosphinyl)propionic acid sodium salt

HRID 1028257Notes

Reaction equation

HRID 1028257 reaction equation
[CH2:1]([P:3]([OH:10])([CH2:5][CH2:6][C:7]([OH:9])=[O:8])=[O:4])[CH3:2].[OH-].[Na+:12]>O>[Na+:12].[CH2:1]([P:3]([OH:10])([CH2:5][CH2:6][C:7]([O-:9])=[O:8])=[O:4])[CH3:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 190110643-[Ethyl(hydroxy)phosphoryl]propanoic acid

Product 1

HCID 1317314203-(Ethylhydroxyphosphinyl)propionic acid sodium saltYield 110.6%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

498 g (3 mol) of 3-(ethylhydroxyphosphinyl)propionic acid (produced as in Example 15) are dissolved in 860 g of water and initially charged into a 5 l five-neck flask equipped with thermometer, reflux condenser, high-performance stirrer and dropping funnel and neutralized with about 480 g (6 mol) of 50% sodium hydroxide solution. The water is subsequently distilled off in vacuo to leave 624 g (99% of theory) of 3-(ethylhydroxyphosphinyl)propionic acid sodium salt as a solid material.

Workup

  1. additioninitially charged into a 5 l five-neck flask
  2. customequipped with thermometer
  3. temperaturereflux condenser, high-performance stirrer
  4. distillationThe water is subsequently distilled off in vacuo

Sources & evidence

ORD record
ord-6afdf596a6d1457cb4cb817f2be2ed67
Source dataset
uspto-grants-2014_05
Patent number
US08735477B2

Reaction notes

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