反应详情

498 g (3 mol) of 3-(ethylhydroxyphosphinyl)propionic acid (produced as in Example 15) are dissolved in 860 g of water and initially charged into a 5 l five-neck flask equipped with thermometer, reflux condenser, high-performance stirrer and dropping funnel and neutralized with about 480 g (6 mol) of 50% sodium hydroxide solution. The water is subsequently distilled off in vacuo to leave 624 g (99% of theory) of 3-(ethylhydroxyphosphinyl)propionic acid sodium salt as a solid material.

1. additioninitially charged into a 5 l five-neck flask
2. customequipped with thermometer
3. temperaturereflux condenser, high-performance stirrer
4. distillationThe water is subsequently distilled off in vacuo