Phenyl glycidyl ether → HCID 71253974, compound

HRID 1028313Notes

Reaction equation

HRID 1028313 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6]1[CH:11]=[N:12][C:13]([C:15]([O:17][CH2:18][CH3:19])=[O:16])=[CH:14][C:5]2=1.[O:20]([CH2:27][CH:28]1[CH2:30][O:29]1)[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([CH2:30][CH:28]([OH:29])[CH2:27][O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)[C:6]1[CH:11]=[N:12][C:13]([C:15]([O:17][CH2:18][CH3:19])=[O:16])=[CH:14][C:5]2=1

Participants

3

Reactant 2

HCID 31217Phenyl glycidyl etherHCID 13037312ethyl 6-bromo-9H-pyrido[3,4-b]indole-3-carboxylate

Product 1

HCID 71253974HCID 71253974, compound

Procedure

Following Representative Procedure 1, the title compound ethyl 6-bromo-9-(2-hydroxy-3-phenoxypropyl)-9H-pyrido[3,4-b]indole-3-carboxylate was prepared from ethyl 6-bromo-9H-pyrido[3,4-b]indole-3-carboxylate and phenoxymethyloxirane in 71% yield.

Sources & evidence

ORD record
ord-a778a594e2d84519b95d574a8dae3abf
Source dataset
uspto-grants-2014_05
Patent number
US08735440B2

Reaction notes

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