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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1028348Generated: October 30, 2026

1-(2,3-Xylyl)piperazine → 3-(2-(4-(2,3-dimethylphenyl) piperazine-1-yl)ethyl)-2-ethylquinazoline-4(3H)-one

https://huagongshe.com/reaction/1028348

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2,3-Xylyl)piperazineHCID 70541—
Reactant2-ethyl-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazine-1-yl)ethyl)quinazoline-4(3H)-oneHCID 66825186—
Product3-(2-(4-(2,3-dimethylphenyl) piperazine-1-yl)ethyl)-2-ethylquinazoline-4(3H)-oneHCID 56944112—

Reaction Steps

This compound was prepared in compliance with the procedure described in 7d, using 1-(2,3-dimethylphenyl)piperazine instead of 1-(3-(trifluoromethyl)phenyl)piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08735578B2
Source datasetuspto-grants-2014_05
ORD IDord-81ea07532a9f434c9c8a04d2f15938e5
Source noteuspto-grants-2014_05