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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1028350Generated: November 2, 2026

1-(2-Ethoxyphenyl)piperazine → 2-ethyl-3-(2-(4-(2-ethoxyphenyl) piperazine-1-yl)ethyl)quinazoline-4(3H)-one

https://huagongshe.com/reaction/1028350

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Ethoxyphenyl)piperazineHCID 83357—
Reactant2-ethyl-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazine-1-yl)ethyl)quinazoline-4(3H)-oneHCID 66825186—
Product2-ethyl-3-(2-(4-(2-ethoxyphenyl) piperazine-1-yl)ethyl)quinazoline-4(3H)-oneHCID 56944211—

Reaction Steps

This compound was prepared in compliance with the procedure described in 7d, using 1-(2-ethoxyphenyl)piperazine instead of 1-(3-(trifluoromethyl)phenyl)piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08735578B2
Source datasetuspto-grants-2014_05
ORD IDord-569679633b59466691189943f90a21d6
Source noteuspto-grants-2014_05