HCID 58036788, compound → HCID 58036799, compound

Participants

Reaction Steps

To a stirred solution of 8-diphenylphosphinoyl-2-phenyl-1,2-dihydroquinoline (8) (1.2 g, 2.95 mmol) in EtOAc (40 mL) was added Pd/C (1.2 g, 100 wt %) and the suspension was stirred overnight at room temperature. The mixture was then filtered over celite and evaporated to give 9 (1.19 g) quantitatively as a white solid. 1H NMR (400.13 MHz, CDCl3) δ 8.63 (dd, 1H, J=14.0, 7.2 Hz, C7—H), 8.16 (dd, 1H, J=8.8, 1.2 Hz, C5—H), 7.86 (1H, d, J=8.4 Hz, C3—H), 7.91 (dd, 4H, J=12.4, 7.2 Hz, Ph-H), 7.81 (dd, 1H, J=8.4 Hz, C4—H), 7.65 (td, 1H, J=8.0, 2.0 Hz, C6—H), 7.5-7.2 (m, 11H, Ph-H) ppm; 13C NMR (100.61 MHz, CDCl3) δ 156.2, 147.4 (d, J=6.1 Hz), 138.4, 137.7 (d, J=7.1 Hz), 136.8, 134.3, 133.2, 132.2, 132.1, 131.9, 131.0, 129.3, 128.3, 128.0, 127.8, 127.4, 125.9, 125.7, 118.7 ppm; 31P NMR (161.97 MHz, CDCl3) δ 27.7 ppm.

Provenance & Evidence