o-Chloroacetanilide → 1-(2-chlorophenyl)-2-methyl-1H-benzimidazole

Participants

Reaction Steps

The title compound was prepared with the analogous procedure described in example 1 using 1-Iodo-2-nitrobenzene (124 mg, 0.5 mmol) and N-(2-chlorophenyl)-acetamide (102 mg, 0.6 mmol) as starting materials to yield the title compound as a yellow solid (74 mg, 61%). 1H NMR (DMSO) δ 2.63 (s, 3 H), 7.34 (d, J=7.9 Hz, 1 H), 7.41 (t, J=7.9 Hz, 1 H), 7.48 (t, J=7.9 Hz, 1 H), 7.64 (d, J=8.6 Hz, 2 H), 7.82 (d, J=7.9 Hz, 1 H), 7.92 (d, J=8.6 Hz, 2 H).

Provenance & Evidence