化工社化工社 化学情報印刷レポート · 研究参考用
Acetanilide → 5-Fluoro-2-methyl-1-phenyl-1H-benzoimidazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetanilide | HCID 904 | — |
| 反応物 | 1-Bromo-4-fluoro-2-nitrobenzene | HCID 2773383 | — |
| 生成物 | 5-Fluoro-2-methyl-1-phenyl-1H-benzoimidazole | HCID 25216869 | 61% |
反応手順
The title compound was prepared with the analogous procedure described in example 3 using 1-Bromo-4-fluoro-2-nitrobenzene and N-phenylacetamide (81 mg, 0.6 mmol) as starting materials to yield the title compound as brown solid (69 mg, 61%). 1H NMR (DMSO) δ 2.49 (s, 3 H), 7.17-7.32 (m, 2 H), 7.61-7.73 (m, 6 H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08735586B2 |
| 出典データセット | uspto-grants-2014_05 |
| ORD ID | ord-2a3dc422c3d043f981b6dabd057aa724 |
| 出典メモ | uspto-grants-2014_05 |