HCID 58493959, compound → HCID 58493995, compound

HRID 1028433Notes

Reaction equation

HRID 1028433 reaction equation
[C:1]([C:5]1[CH:6]=[C:7]([N+:17]([O-])=O)[C:8]([O:15][CH3:16])=[C:9]([S:11]([CH3:14])(=[O:13])=[O:12])[CH:10]=1)([CH3:4])([CH3:3])[CH3:2]>[Pd].CO>[C:1]([C:5]1[CH:10]=[C:9]([S:11]([CH3:14])(=[O:12])=[O:13])[C:8]([O:15][CH3:16])=[C:7]([CH:6]=1)[NH2:17])([CH3:4])([CH3:2])[CH3:3]

Participants

4

Reactant 1

HCID 58493959HCID 58493959, compound

Product 1

HCID 58493995HCID 58493995, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A mixture of 14.5 g 5-tert-butyl-1-methanesulphonyl-2-methoxy-3-nitro-benzene, 3.0 g 10% palladium on charcoal and 250 ml of methanol is shaken for 6 h at ambient temperature under a hydrogen atmosphere (50 psi). Then the catalyst is filtered off and the filtrate is evaporated to dryness.

Workup

  1. filtrationThen the catalyst is filtered off
  2. customthe filtrate is evaporated to dryness

Sources & evidence

ORD record
ord-ed29a12b8ce842b9b0f33b63f14139a0
Source dataset
uspto-grants-2014_05
Patent number
US08735579B2

Reaction notes

Loading…