Hydrazine hydrate (1:1) → HCID 69189942, compound

Participants

Reaction Steps

To a solution of Example 11C (770 mg, 1.69 mmol) in methylene chloride (20 mL) and ethanol (2 min) was added hydrazine monohydrate (540 μL, 11.1 mmol, 6.6 eq.) at room temperature. The mixture was stirred at room temperature overnight. The mixture was filtered. The filtrate was concentrated. The residue was dissolved in methylene chloride again, which was filtered and the filtrate was concentrated to give the title compound (615 mg), which was used without further purification.

Provenance & Evidence