1,3-Dibromo-5,5-dimethylhydantoin → Diethyl dioxobutanedioate

Participants

Reaction Conditions

Reaction Steps

L-Tartaric acid diethyl ester (50.0 g), acetic acid (900 ml), 1,3-dibromo-5,5-dimethylhydantoin (149.1 g) and 2,2′-azobis(4-methoxy-2,4-dimethylvaleronitrile) (750 mg) were mixed, and the reaction solution was stirred at 70° C. for 2 hours, followed by stirring at room temperature for 16 hours. The reaction solution was concentrated under reduced pressure until its volume became approximately 300 ml to obtain a solution of diethyl dioxobutanedioate in acetic acid as a yellow liquid.

Provenance & Evidence