Benzene → 3-Nitro-1-phenylpropan-1-one

HRID 1028877Notes

Reaction equation

[N+:1]([CH2:4][CH2:5][C:6](Cl)=[O:7])([O-:3])=[O:2].[CH:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>>[N+:1]([CH2:4][CH2:5][C:6]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:7])([O-:3])=[O:2]

Participants

Reactant 2

HCID 241Benzene

HCID 126886603-Nitropropanoyl chloride

Product 1

HCID 5694913-Nitro-1-phenylpropan-1-one

Procedure

The title compound was prepared from benzene and 3-nitropropanoyl chloride, according to example 2, affording compound (15) with 78% yield, mp 72-74° C.

Sources & evidence

ORD record: ord-7244688d4d6f41d39c335201b7ce7da2
Source dataset: uspto-grants-2014_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08735627B2

Reaction notes

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