Octanoyl chloride → HCID 56968059, compound

HRID 1028882Notes

Reaction equation

[CH3:1][C:2]1([CH3:19])[O:7][CH2:6][C:5]([N+:16]([O-:18])=[O:17])([CH2:8][CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH2:4][O:3]1.[C:20](Cl)(=[O:28])[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27]>>[CH3:1][C:2]1([CH3:19])[O:3][CH2:4][C:5]([CH2:8][CH2:9][C:10]2[CH:15]=[CH:14][C:13]([C:20](=[O:28])[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])=[CH:12][CH:11]=2)([N+:16]([O-:18])=[O:17])[CH2:6][O:7]1

Participants

Reactant 2

HCID 8124Octanoyl chloride

HCID 56968061HCID 56968061, compound

Product 1

HCID 56968059HCID 56968059, compound

Procedure

The title compound was prepared from 2-dimethyl-5-nitro-5-phenethyl-1,3-dioxane (20) and octanoyl chloride, according to example 2, affording compound (21) with 68% yield, which was used at the next step without additional purification.

Sources & evidence

ORD record: ord-379550e1e6354940a7bd4aa349ca8ad1
Source dataset: uspto-grants-2014_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08735627B2

Reaction notes

Loading…