Water → HCID 86622009, compound

Participants

Reaction Steps

Dess-Martin periodinane (971 mg, 2.3 mmol) was added to a solution of intermediate (5b) (474 mg, 0.8 mmol) in DCM (20 mL) at room temperature. After 30 minutes, water (20 mL) and saturated aqueous sodium thiosulfate (20 mL) was added. The mixture was extracted with DCM (3×30 mL), washed with saturated aqueous NaCl (20 mL), dried over MgSO4, and concentrated in vacuo. Silica gel chromatography gave intermediate (5c) as a white solid (411 mg).

Provenance & Evidence