Ammonium formate → HCID 58168380, compound

Participants

Reaction Conditions

Reaction Steps

Compound 160 (45 mg, 0.14 mmol), ammonium formate (100 mg, 1.60 mmol), and Pd/carbon (100 mg, 10% by weight, wet) were suspended in dioxane (2 mL), and stirred for 4 h at 70° C. The reaction mixture was filtered, and purified via Biotage eluting with a gradient of 25 to 75 EtOAc in hexanes to provide 162 (14 mg, 31% yield) as a white solid. LC-MS (M+H=331, obsd.=331).

Provenance & Evidence