1-Ethynyl-4-methoxybenzene → HCID 58168239, compound

Participants

Reaction Conditions

Reaction Steps

The title compound was synthesized according to the procedure described for the preparation of Example 160 using Compound 83 (100 mg, 0.43 mmol) and 1-Ethynyl-4-methoxy-benzene (86 mg, 0.65 mmol) was then added, and the resulting solution was stirred for 3 h at 100° C. The reaction mixture was diluted with EtOAc/H2O. The resulting precipitate was filtered, washed with EtOAc/H2O, and dried under vacuum to provide 163 (101 mg, 71% yield) as a white solid. LC-MS (M+H=327, obsd.=327).

Provenance & Evidence