HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Trifluoromethyl)aniline → HCID 58168134, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Trifluoromethyl)aniline | HCID 7375 | — |
| Reactant | 1-Chlorobenzo[C][1,8]naphthyridin-6(5H)-one | HCID 58168008 | — |
| Product | HCID 58168134 | HCID 58168134 | 34% |
Reaction Steps
The title compound was synthesized according to the procedure described for the preparation of Example 188 using Compound 83 (100 mg, 0.43 mmol) and 3-(trifluoromethyl)aniline (140 mg, 0.87 mmol) to provide 194 (52 mg, 34% yield) as a white solid. LC-MS (M+H=356, obsd.=356).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08735584B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-c508dda131b94e5480f92dab9009c6b3 |
| Source note | uspto-grants-2014_05 |