HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2-Difluoro-1,3-dioxaindan-4-amine → HCID 58168192, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2-Difluoro-1,3-dioxaindan-4-amine | HCID 2736891 | — |
| Reactant | 1-Chlorobenzo[C][1,8]naphthyridin-6(5H)-one | HCID 58168008 | — |
| Product | HCID 58168192 | HCID 58168192 | 77.2% |
Reaction Steps
The title compound was synthesized according to the procedure described for the preparation of Example 188 using Compound 83 (100 mg, 0.43 mmol) and 2,2-difluoro-benzo[1,3]dioxol-4-ylamine (150 mg, 0.87 mmol) to provide 196 (122 mg, 77% yield) as a white solid. LC-MS (M+H=368, obsd.=368).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08735584B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-9298ac35552149928b82e794018741d1 |
| Source note | uspto-grants-2014_05 |