4-Chloro-3-iodopyridin-2-amine → HCID 58168150, compound

Participants

Reaction Steps

The title compound was synthesized according to the procedure described for the preparation of Example 1 using 4-chloro-3-iodopyridin-2-amine (350 mg, 1.38 mmol) and 5-(3-morpholin-4-yl-propoxy)-2-(4,4,5,5-tetramethyl[1,3,2]-dioxaborolan-2-yl)-benzoic acid methyl ester (697 mg, 1.72 mmol) to provide 226 (120 mg, 23% yield) as a white solid. LC-MS (M+H=374, obsd.=374).

Provenance & Evidence