4-Aminoacetanilide → HCID 69812399, compound

HRID 1029197Notes

Reaction equation

HRID 1029197 reaction equation
Cl[C:2]1[CH:16]=[CH:15][C:5]2[C:6](=[O:14])[NH:7][C:8]3[C:13]([C:4]=2[CH:3]=1)=[CH:12][CH:11]=[CH:10][N:9]=3.[NH2:17][C:18]1[CH:23]=[CH:22][C:21]([NH:24][C:25](=[O:27])[CH3:26])=[CH:20][CH:19]=1>>[O:14]=[C:6]1[C:5]2[CH:15]=[CH:16][C:2]([NH:17][C:18]3[CH:19]=[CH:20][C:21]([NH:24][C:25](=[O:27])[CH3:26])=[CH:22][CH:23]=3)=[CH:3][C:4]=2[C:13]2[C:8](=[N:9][CH:10]=[CH:11][CH:12]=2)[NH:7]1

Participants

3

Reactant 2

HCID 312304-AminoacetanilideHCID 581682989-chloro-5H-benzo[c][1,8]naphthyridin-6-one

Product 1

HCID 69812399HCID 69812399, compoundYield 17%

Procedure

The title compound was synthesized according to the procedure described for the preparation of Example 231 using 6 (50 mg, 0.22 mmol) and N-(4-Amino-phenyl)-acetamide (38 mg, 0.33 mmol) to provide 234 (10 mg, 17% yield) as a brown solid. LC-MS (M+H=345, obsd.=345).

Workup

  1. customThe title compound was synthesized

Sources & evidence

ORD record
ord-67bb964ec6f94079acdcd3391e66ac65
Source dataset
uspto-grants-2014_05
Patent number
US08735584B2

Reaction notes

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