HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoromethyl toluidine → HCID 58168167, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoromethyl toluidine | HCID 2735932 | — |
| Reactant | 9-chloro-5H-benzo[c][1,8]naphthyridin-6-one | HCID 58168298 | — |
| Product | HCID 58168167 | HCID 58168167 | 28.3% |
Reaction Steps
The title compound was synthesized according to the procedure described for the preparation of Example 231 using 6 (50 mg, 0.22 mmol) and 2-methyl-3-trifluoromethyl-phenylamine (0.03 mL, 0.33 mmol) to provide 237 (23 mg, 28% yield) as a brown solid. LC-MS (M+H=370, obsd.=370).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08735584B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-14a134332e3b40c2bc8501ec69b1332f |
| Source note | uspto-grants-2014_05 |