4-Ethylaniline → HCID 58168052, compound

HRID 1029207Notes

Reaction equation

HRID 1029207 reaction equation
Cl[C:2]1[CH:16]=[CH:15][C:5]2[C:6](=[O:14])[NH:7][C:8]3[C:13]([C:4]=2[CH:3]=1)=[CH:12][CH:11]=[CH:10][N:9]=3.[CH2:17]([C:19]1[CH:25]=[CH:24][C:22]([NH2:23])=[CH:21][CH:20]=1)[CH3:18]>>[CH2:17]([C:19]1[CH:25]=[CH:24][C:22]([NH:23][C:2]2[CH:16]=[CH:15][C:5]3[C:6](=[O:14])[NH:7][C:8]4[C:13]([C:4]=3[CH:3]=2)=[CH:12][CH:11]=[CH:10][N:9]=4)=[CH:21][CH:20]=1)[CH3:18]

Participants

3

Reactant 2

HCID 115044-EthylanilineHCID 581682989-chloro-5H-benzo[c][1,8]naphthyridin-6-one

Product 1

HCID 58168052HCID 58168052, compoundYield 15%

Procedure

The title compound was synthesized according to the procedure described for the preparation of Example 231 using 6 (100 mg, 0.43 mmol) and 4-ethylaniline (0.08 mL, 0.65 mmol) to provide 244 (4 mg, 15% yield) as a dark brown solid. LC-MS (M+H (parent)=316, obsd.=316).

Workup

  1. customThe title compound was synthesized

Sources & evidence

ORD record
ord-73a5a6d7dfe943dab929c44f21fe9def
Source dataset
uspto-grants-2014_05
Patent number
US08735584B2

Reaction notes

Loading…