3-Amino-4-methylbiphenyl → HCID 58167952, compound

Participants

Reaction Steps

The title compound was synthesized according to the procedure described for the preparation of Example 231 using 6 (100 mg, 0.43 mmol) and 5-phenyl-o-toluidine (119 mg, 0.65 mmol) to provide 245 (25 mg, 14% yield) as a brown solid. LC-MS (M+H (parent)=378, obsd.=378). 1H NMR (400 MHz, d6-DMSO): δ 11.63 (s, 1H), 8.45 (m, 2H), 8.37 (d, 1H), 8.13 (d, 1H), 7.63 (m, 3H), 7.58 (s, 1H), 7.44 (m, 4H), 7.34 (m, 1H), 7.26 (m, 1H), 7.14 (dd, 1H). 2.28 (s, 3H).

Provenance & Evidence