化工社化工社 化学情報印刷レポート · 研究参考用
5,6,7,8-Tetrahydro-2-naphthylamine → 9-(5,6,7,8-Tetrahydro-naphthalen-2-ylamino)-5H-benzo[c][1,8]naphthyridin-6-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5,6,7,8-Tetrahydro-2-naphthylamine | HCID 75193 | — |
| 反応物 | HCID 58168298 | HCID 58168298 | — |
| 生成物 | 9-(5,6,7,8-Tetrahydro-naphthalen-2-ylamino)-5H-benzo[c][1,8]naphthyridin-6-one | HCID 58168221 | 65.2% |
反応手順
The title compound was synthesized according to the procedure described for the preparation of Example 231 using 6 (50 mg, 0.22 mmol) and 5,6,7,8-tetrahydro-2-naphthylamine (96 mg; 0.65 mmol) to provide 248 (49 mg, 27% yield) as a brown solid. LC-MS (M+H (parent)=343, obsd.=343).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08735584B2 |
| 出典データセット | uspto-grants-2014_05 |
| ORD ID | ord-4d044e3de9e44f469321f7a065894345 |
| 出典メモ | uspto-grants-2014_05 |