Sodium Hydroxide → HCID 58168185, compound

Participants

Reaction Conditions

Reaction Steps

4-[(6-Oxo-5,6-dihydrobenzo[c]-1,8-naphthyridin-9-yl)amino]benzonitrile (40 mg, 0.13 mmol) and NaOH (1.3 mL, 1.00 M; 1.28 mmol) were suspended in dioxane (2 mL), and stirred for 120 min at 120° C. in the microwave. The crude material was purified directly via prep-LC-MS to provide 249 (2 mg, 6% yield) as a brown solid. LC-MS (M+H=331 obsd.=331).

Provenance & Evidence