2-Methylphenylacetylene → HCID 58168216, compound

Participants

Reaction Steps

The title compound was synthesized according to the procedure described for the preparation of Example 160 using 83 (100 mg, 0.43 mmol) and 2-ethynyltoluene (0.08 mL, 0.65 mmol) to provide 257 (88 mg, 65% yield) as a tan solid. LC-MS (M+H=311 obsd.=311). 1H NMR (400 MHz, d6-DMSO): δ 9.79 (d, 1H), 8.48 (d, 1H), 8.42 (dd, 1H), 7.95 (m, 1H), 7.75 (m, 2H), 7.46 (m, 3H), 7.36 (m, 1H), 2.61 (s, 3H).

Provenance & Evidence