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HRID1029224

反应详情

EQUATION

反应方程式

HRID 1029224 的结构方程式

REACTANTS

反应物

2
结构：Nc1nccc(Cl)c1I
HCID22936596

4-Chloro-3-iodopyridin-2-amine

C5H4ClIN2

结构：COC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)c(C(=O)OC)c1
HCID68648791

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)c1ccc2c(c1)c(=O)[nH]c1nccc(Cl)c12
HCID58168369

未命名化合物

收率 48.5%

PROCEDURE

实验过程

The title compound was synthesized according to the procedure described for the preparation of Example 1 using 4-chloro-3-iodopyridin-2-amine (510 mg, 2.0 mmol) and dimethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isophthalate (705 mg, 2.2 mmol) to provide 266 (280 mg, 48% yield) as a white solid. LC-MS (M+H=289, obsd.=289).

WORKUP

后处理

  1. customThe title compound was synthesized