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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1029233Generated: October 25, 2026

Benzamide, N-(4-aminophenyl)- → N-(4-(8-Chloro-6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridin-1-ylamino)phenyl)benzamide

https://huagongshe.com/reaction/1029233

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzamide, N-(4-aminophenyl)-HCID 87196—
Reactant1,8-dichloro-5H-benzo[c][1,8]naphthyridin-6-oneHCID 69810024—
ProductN-(4-(8-Chloro-6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridin-1-ylamino)phenyl)benzamideHCID 44205715—

Reaction Steps

The title compound was synthesized according to the procedure described for the preparation of Example 267 using 1,8-dichloro-5H-benzo[c][1,8]naphthyridin-6-one and N-(4-aminophenyl)benzamide to provide 275. LC-MS (M+H=442, obsd.=442).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08735584B2
Source datasetuspto-grants-2014_05
ORD IDord-8020402224434897941985ae40b73c16
Source noteuspto-grants-2014_05