4-Chloro-3-iodopyridin-2-amine → HCID 58167975, compound

HRID 1029235Notes

Reaction equation

HRID 1029235 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([NH2:8])[C:3]=1I.[CH3:10][O:11][C:12](=[O:32])[C:13]1[CH:22]=[CH:21][C:16]([C:17](OC)=[O:18])=[CH:15][C:14]=1B1OC(C)(C)C(C)(C)O1>>[Cl:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]2[C:3]=1[C:21]1[CH:22]=[C:13]([C:12]([O:11][CH3:10])=[O:32])[CH:14]=[CH:15][C:16]=1[C:17](=[O:18])[NH:8]2

Participants

3

Reactant 2

HCID 229365964-Chloro-3-iodopyridin-2-amineHCID 68648457HCID 68648457, compound

Product 1

HCID 58167975HCID 58167975, compound

Procedure

The title compound was synthesized according to the procedure described for the preparation of Example 1 using 4-chloro-3-iodopyridin-2-amine and 2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-terephthalic acid dimethyl ester to provide 277. LC-MS (M+H=289, obsd.=289).

Workup

  1. customThe title compound was synthesized

Sources & evidence

ORD record
ord-46405d7285294c70903be3fbc6f41fb6
Source dataset
uspto-grants-2014_05
Patent number
US08735584B2

Reaction notes

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