HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzamide, N-(3-aminophenyl)- → 1-(3-Benzamidophenylamino)-N-(2-(dimethylamino)ethyl)-6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridine-9-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzamide, N-(3-aminophenyl)- | HCID 72896 | — |
| Reactant | 1-Chloro-N-(2-(dimethylamino)ethyl)-6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridine-9-carboxamide | HCID 69810673 | — |
| Product | 1-(3-Benzamidophenylamino)-N-(2-(dimethylamino)ethyl)-6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridine-9-carboxamide | HCID 69811630 | — |
Reaction Steps
The title compound was synthesized according to the procedure described for the preparation of Example 267 using 296 (40 mg, 0.12 mmol) and N-(3-amino-phenyl)-benzamide to provide 301. LC-MS (M+H=521, obsd.=521).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08735584B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-e287c48075f84540a658f3b3ba548399 |
| Source note | uspto-grants-2014_05 |