Aniline → HCID 44206391, compound

HRID 1029243Notes

Reaction equation

HRID 1029243 reaction equation
[O:1]=[C:2]1[C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=2[C:9]2[C:4](=[N:5][CH:6]=[CH:7][C:8]=2[NH:16][C:17]2[CH:22]=[CH:21][C:20]([CH2:23][C:24]([OH:26])=O)=[CH:19][CH:18]=2)[NH:3]1.[NH2:27][C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1>>[O:1]=[C:2]1[C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=2[C:9]2[C:4](=[N:5][CH:6]=[CH:7][C:8]=2[NH:16][C:17]2[CH:22]=[CH:21][C:20]([CH2:23][C:24]([NH:27][C:28]3[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=3)=[O:26])=[CH:19][CH:18]=2)[NH:3]1

Participants

3

Reactant 2

HCID 6115AnilineHCID 58168100HCID 58168100, compound

Product 1

HCID 44206391HCID 44206391, compound

Procedure

The title compound was synthesized according to the procedure described for the preparation of Example 300 using 302 (50 mg, 0.14 mmol), and aniline to provide 303. LC-MS (M+H=421, obsd.=421).

Workup

  1. customThe title compound was synthesized

Sources & evidence

ORD record
ord-aa8f01db92e1491899df3906c4dbeeb9
Source dataset
uspto-grants-2014_05
Patent number
US08735584B2

Reaction notes

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