2-(Trifluoromethyl)benzylamine → HCID 58168278, compound

HRID 1029245Notes

Reaction equation

HRID 1029245 reaction equation
[CH2:1]([NH:8][C:9]([C:11]1[N:12]([CH3:32])[CH:13]=[C:14]([NH:16][C:17]2[CH:26]=[CH:25][N:24]=[C:23]3[C:18]=2[C:19]2[CH:31]=[CH:30][CH:29]=[CH:28][C:20]=2[C:21](=[O:27])[NH:22]3)[CH:15]=1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:33][C:34]([F:44])([F:43])C1C=CC=CC=1CN>>[CH3:32][N:12]1[CH:13]=[C:14]([NH:16][C:17]2[CH:26]=[CH:25][N:24]=[C:23]3[C:18]=2[C:19]2[CH:31]=[CH:30][CH:29]=[CH:28][C:20]=2[C:21](=[O:27])[NH:22]3)[CH:15]=[C:11]1[C:9]([NH:8][CH2:1][C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][C:7]=1[C:34]([F:44])([F:43])[F:33])=[O:10]

Participants

3

Reactant 2

HCID 764472-(Trifluoromethyl)benzylamineHCID 58167955HCID 58167955, compound

Product 1

HCID 58168278HCID 58168278, compound

Procedure

The title compound was synthesized according to the procedure described for the preparation of Example 300 using the carboxylic acid intermediate from example 310 and 2-trifluoromethyl-benzylamine to provide 311. LC-MS (M+H=492, obsd.=492).

Workup

  1. customThe title compound was synthesized

Sources & evidence

ORD record
ord-a683d4df7c694dd3af6c6954d3265dfc
Source dataset
uspto-grants-2014_05
Patent number
US08735584B2

Reaction notes

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