3-Fluoroaniline → HCID 58168349, compound

HRID 1029247Notes

Reaction equation

HRID 1029247 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([NH:9][C:10](=[O:33])[CH2:11][C:12]2[NH:16][N:15]=[C:14]([NH:17][C:18]3[CH:27]=[CH:26][N:25]=[C:24]4[C:19]=3[C:20]3[CH:32]=[CH:31][CH:30]=[CH:29][C:21]=3[C:22](=[O:28])[NH:23]4)[CH:13]=2)[CH:5]=[CH:6][C:7]=1F.FC1C=C(C=CC=1)N>>[F:1][C:2]1[CH:3]=[C:4]([NH:9][C:10](=[O:33])[CH2:11][C:12]2[NH:16][N:15]=[C:14]([NH:17][C:18]3[CH:27]=[CH:26][N:25]=[C:24]4[C:19]=3[C:20]3[CH:32]=[CH:31][CH:30]=[CH:29][C:21]=3[C:22](=[O:28])[NH:23]4)[CH:13]=2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 97423-FluoroanilineHCID 58168312HCID 58168312, compound

Product 1

HCID 58168349HCID 58168349, compound

Procedure

The title compound was synthesized according to the procedure described for the preparation of Example 300 using the carboxylic acid intermediate from example 313 and 3-fluoroaniline to provide 314. LC-MS (M+H=429, obsd.=429).

Workup

  1. customThe title compound was synthesized

Sources & evidence

ORD record
ord-fb2397033b234607b9746a28b8e4282f
Source dataset
uspto-grants-2014_05
Patent number
US08735584B2

Reaction notes

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