HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl Isocyanate → HCID 58168115, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl Isocyanate | HCID 12228 | — |
| Reactant | 1-(4-Piperidinylamino)benzo[c][1,8]naphthyridin-6(5H)-one | HCID 58168194 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | HCID 58168115 | HCID 58168115 | 44% |
Reaction Steps
358 (50 mg, 0.17 mmol) and isocyanatomethane (15 mg, 0.25 mmol) were suspended in DCE (2 mL), and stirred overnight at room temperature. The crude material was purified directly via HPLC to provide 359 (26 mg, 44% yield) as a solid. LC-MS (M+H=351, obsd.=351).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08735584B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-65b9381faaea4d27a822f904160047d8 |
| Source note | uspto-grants-2014_05 |