Chloroacetanilide → HCID 69814285, compound

HRID 1029260Notes

Reaction equation

HRID 1029260 reaction equation
C1(CC([N:10]2[CH2:14][CH2:13][CH:12]([NH:15][C:16]3[CH:25]=[CH:24][N:23]=[C:22]4[C:17]=3[C:18]3[CH:30]=[CH:29][CH:28]=[CH:27][C:19]=3[C:20](=[O:26])[NH:21]4)[CH2:11]2)=O)C=CC=CC=1.Cl[CH2:32][C:33]([NH:35][C:36]1[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1)=[O:34]>>[O:26]=[C:20]1[C:19]2[CH:27]=[CH:28][CH:29]=[CH:30][C:18]=2[C:17]2[C:22](=[N:23][CH:24]=[CH:25][C:16]=2[NH:15][CH:12]2[CH2:13][CH2:14][N:10]([CH2:32][C:33]([NH:35][C:36]3[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=3)=[O:34])[CH2:11]2)[NH:21]1

Participants

3

Reactant 2

HCID 11485ChloroacetanilideHCID 58168200HCID 58168200, compound

Product 1

HCID 69814285HCID 69814285, compound

Procedure

The title compound was synthesized according to the procedure described for the preparation of Example 370 using the amine intermediate from example 369 and 2-chloro-N-phenylacetamide to provide 371. LC-MS (M+H=414, obsd.=414).

Workup

  1. customThe title compound was synthesized

Sources & evidence

ORD record
ord-9ce7fc2603af4d46a4534aebefaa7522
Source dataset
uspto-grants-2014_05
Patent number
US08735584B2

Reaction notes

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