4-Chlorobenzylamine → HCID 58168303, compound

Participants

Reaction Steps

The title compound was synthesized according to the procedure described for the preparation of Example 448 using 6 (100 mg, 0.43 mmol) and (4-chloro-phenyl)methanamine (245 mg, 1.73 mmol) to provide 452 (20 mg, 14% yield) as a white powder. LC-MS (M+H=337, obsd.=337). 1H NMR (400 MHz, DMSO-D6) δ 11.49 (s, 1H), 8.56 (d, J=8.3, 1H), 8.41 (s, 1H), 7.99 (d, J=8.8, 1H), 7.44 (dd, J=8.5, 22.3, 2H), 7.37 (s, 2H), 7.25 (d, J=12.5, 2H), 6.95 (s, 1H), 4.51 (s, 2H).

Provenance & Evidence