1-Pyrrolidineethanamine → HCID 58168256, compound

Participants

Reaction Steps

The title compound was synthesized according to the procedure described for the preparation of Example 456 using 6 (100 mg, 0.43 mmol) and 2-pyrrolidin-1-ylethanamine (0.22 mL, 1.73 mmol) to provide 474 (24 mg, 18% yield) as a white powder. LC-MS (M+H=309, obsd.=309). 1H NMR (400 MHz, DMSO-D6) δ 11.59 (s, 1H), 9.65 (s, 1H), 8.75 (d, J=8.0, 1H), 8.39 (m, 1H), 8.05 (d, J=8.7, 1H), 7.42 (s, 1H), 7.28 (dd, J=4.6, 7.9, 1H), 6.95 (d, J=8.7, 1H), 3.65 (s, 4H), 3.41 (s, 2H), 3.10 (s, 2H), 1.96 (d, J=59.8, 4H).

Provenance & Evidence