HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 5-Chloro-2-(methylthio)benzothiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1H-Pyrazol-5-ol, 3-methyl-1-phenyl- | HCID 70335 | — |
| Reactant | 3-[5-Chloro-2-(methylthio)-1,3-benzothiazol-3-ium-3-yl]-1-propanesulfonate | HCID 4383736 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5-Chloro-2-(methylthio)benzothiazole | HCID 645746 | — |
Reaction Steps
3-Methyl-1-phenylpyrazolin-5-one (1.045 g) was mixed with 2.03 g (0.006 mol) 2-methylthio-5-chloro-3-(3'-sulfopropyl)benzothiazolium, inner salt in 50 ml methanol. Triethylamine (0.62 g) was added. The mixture was stirred for one hour, the solvent evaporated, and the residue dissolved in isopropanol. The resulting solution was treated with 0.6 g KOAc in methanol to precipitate the dye. Filtering yielded 2.17 g (72%), mp 271°-276° C., λmax=383 (ε=19,000).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05102781 |
| Source dataset | uspto-grants-1992_04 |
| ORD ID | ord-3c95269e58ae498b8021c76427471d47 |
| Source note | uspto-grants-1992_04 |