HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 4-[-3-Methylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Benzothiazolium, 3-methyl-2-(methylthio)-, 4-methylbenzenesulfonate (1:1) | HCID 41464 | — |
| Reactant | 1H-Pyrazol-5-ol, 3-methyl-1-phenyl- | HCID 70335 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-[-3-Methylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-one | HCID 86745611 | — |
Reaction Steps
3-Methyl-1-phenylpyrazolin-5-one (1.74 g, 0.01 mol) was mixed with 3.68 g (0.01 mol) 2-methylthio-3-methylbenzothiazolium tosylate in 25 ml methanol. Triethylamine (1.01 g, 0.01 mol) was added. The mixture was stirred for one hour, then filtered and washed with methanol. After drying the yield was 2.46 g (78%), mp 159°-162° C., λmax=375 (ε=25,000).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05102781 |
| Source dataset | uspto-grants-1992_04 |
| ORD ID | ord-6cbb14defca149e0998b6ab85d6dad14 |
| Source note | uspto-grants-1992_04 |