HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 4-[3-Ethylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1H-Pyrazol-5-ol, 3-methyl-1-phenyl- | HCID 70335 | — |
| Reactant | 3-Ethyl-2-(ethylsulfanyl)-1,3-benzothiazol-3-ium 4-methylbenzene-1-sulfonate | HCID 14090547 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-[3-Ethylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-one | HCID 86745616 | — |
Reaction Steps
3-Methyl-1-phenylpyrazolin-5-one (1.74 g, 0.01 mol) was mixed with a methanol solution of 2-ethylthio-3-ethylbenzothiazolium tosylate. Triethylamine (1.01 g, 0.01 mol) was added. The mixture was stirred for 10 minutes, then concentrated and treated with isopropanol. The mixture was heated to dissolve the product, then water was added to cloud, and the mixture cooled to give crystals: 3.22 g (48%), mp 144°-147.5° C., λmax=379 (ε=25,000).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05102781 |
| Source dataset | uspto-grants-1992_04 |
| ORD ID | ord-b931c63ecf554f069f4279a9ac934fab |
| Source note | uspto-grants-1992_04 |