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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1029457Generated: October 27, 2026

1-(3-Bromopropyl)-4-chlorobenzene → 4-(4-Chlorophenyl)-1-(4-t-butyldiphenylsiloxy phenyl)butanol

https://huagongshe.com/reaction/1029457

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-Bromopropyl)-4-chlorobenzeneHCID 9881136—
Reactant4-((2-Methyl-2-propyl)diphenylsilyloxy)benzaldehydeHCID 11428383—
Product4-(4-Chlorophenyl)-1-(4-t-butyldiphenylsiloxy phenyl)butanolHCID 53857806—

Reaction Steps

Using the procedure of Example 1, Step 2, the Grignard reagent prepared from 1-(3-bromopropyl)-4-chlorobenzene was added to the benzaldehyde of Step 1. The title compound so obtained was used as such in the next step.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05102881
Source datasetuspto-grants-1992_04
ORD IDord-614fc72046d4433ba37b239d2812fe7f
Source noteuspto-grants-1992_04